Functional ultrasound imaging could be 1000x better than fMRI—and it's just getting started
Functional Ultrasound Imaging (fUSI) from scratch
Functional ultrasound imaging (fUSI) captures rapid movies of brain tissue, tracking blood flow changes with up to 20% signal change—far exceeding fMRI's few-percent BOLD. It offers ten times higher linear resolution, 1000x more voxels, and no magnet. I break down the physics and signal processing, from plane-wave transmission to Power Doppler and clutter filtering, and share Python tutorials to make fUSI accessible beyond Matlab. The modality is far from its ceiling.
The percentage signal change measured with fUSI is remarkably high: up to 20% compared to fMRI's few-percent BOLD signal.