A 32-Year-Old With Stage IV Pancreatic Cancer Is Getting a Crowdsourced mRNA Vaccine

Cancer vaccine for Yash, he's diagnosed with stage IV pancreatic cancer

In January 2025, Yashdeep Bindal, 32, was diagnosed with stage IV pancreatic cancer shortly after his daughter Maya was born. The RNA Foundry has published his tumor sequencing data and a lead personalized mRNA vaccine design on GitHub, built from matched-normal DNA and covering 12 mutation, 5 splice, 5 CTA/self, and 2 fusion regions. Researchers can reproduce the design, submit alternative candidates via pull request, and explore directions like MHC class II targeting.

Have a vaccine design for Yash? Submit a pull request.
  1. AsDivyansh

    Complete story here: https://rnafoundry.com/yash/

  2. x1798DE

    He was diagnosed with stage IV pancreatic cancer in January 2025 and he is still alive? Does that mean the vaccine worked? I thought that was a 3-6 month prognosis kind of deal.

    I do hope it works out.

  3. marky1991

    i don't understand, have they administered their vaccine to him already?

    The last treatment update was from over a year ago, what has happened since then?

    The whole thing seems a little disconnected.

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