APSW glues the entire SQLite C API to Python
apsw: Another Python SQLite Wrapper

APSW, Another Python SQLite Wrapper, exposes the complete SQLite C API to CPython 3.10 and later, including full text search, sessions, virtual tables, VFS, JSON, and CArray. It works in synchronous code and all async frameworks. The author recommends the builtin sqlite3 module if you want SQLite to look interchangeable with other database drivers, and APSW when you want to use SQLite fully.
Use APSW when you want to use SQLite fully, and have an improved developer experience.