Taxi drivers rarely die of Alzheimer's – how complex mental maps and spatial reasoning protect your brain

A 2024 study of nearly 9 million U.S. death certificates found that taxi and ambulance drivers have the lowest risk of dying from Alzheimer's among 443 occupations. The key appears to be continuous real-time navigation, which exercises the hippocampus, a brain region vulnerable to Alzheimer's. London taxi drivers, who memorize 25,000 streets, show increased gray matter in this area. This raises questions about whether spatial reasoning in professions like GIS and urban planning offers similar protection, and suggests that mentally demanding spatial tasks could help build cognitive reserve against dementia.
The researchers concluded that the key to reducing the risk of Alzheimer's was not driving itself but continuous real-time navigation: the constant work of locating yourself in space, tracking a destination and updating a mental map as conditions change.