Psilocybin therapy shows early promise in treating anorexia

Could psilocybin be the key to treating anorexia?

Psilocybin therapy shows early promise in treating anorexia

A small pilot study found that psilocybin, combined with talk therapy, rapidly reduced anorexia symptoms and increased motivation to change in women with the disorder. While not a cure-all, the results suggest the psychedelic could kick-start recovery, though experts caution that more research is needed and that the drug isn't without risks.

“People have likened anorexia to a slow suicide. To have that flip to feeling like ‘I want to live and be healthy’ is massive.”
  1. bbayles

    Anecdata, but an acquaintance of mine struggled with lifelong anorexia. Severe enough that he was hospitalized a few times. With great effort he could cling to the bottom of the "normal BMI" range, but his life was generally ruled by the eating disorder - he couldn't have meals with people, he had to do various exercise rituals.

    He was an early participant in one of these psychedelic studies a few years ago. After the first treatment, he said he couldn't really tell if it had any effect. But six months later, he was totally changed - able to function almost normally.

    We should exercise our usual amount of skepticism about miracle treatments, but my hope is that his experience can be replicated.

  2. inigyou

    Psychedelics open your brain up to rewiring in some way, and can be used under direction to treat a lot of things. But of course, people who didn't like the Vietnam War used them recreationally, which is why the US government made them globally illegal.

  3. ulrikrasmussen

    I lost a family member to anorexia, and the only thing I really regret is that I didn't suggest that we try psychedelic therapy now that everything else had failed and things looked pretty grim. I mostly blame myself for not pushing the idea. But I am also angry at the war on drugs which has caused all use of psychoactive drugs to be associated with such taboo.

  4. mikert89

    Psychedelics arent that far from turning your brain off and then turning it back on again

    but anyone i have met that did Psychedelics more than a few times, permanently changed their brain chemistry in a way that was obvious. clearly they are doing some kind of unraveling that doesnt fully bounce back

  5. stephenitis

    I attended a presentation at the maps conference in ‘23(?). The presenter said that the effect was not enduring for those on already on a path to recovery. She hypothesized that the body need nourishment and a lot of ancillary support to sustain that kind of neurological change.

    (I’ll try to search for it when I have free time)

    Psychedelic trips are taxing on the body and I think I agree with the hypothesis nutrients are underestimated in supporting a healthy mind in these states, from personal experience.

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2026-08-05